[1]韩立志　吴光耀.颅内脱髓鞘假瘤磁共振影像表现与代谢物特征分析[J].中国临床神经外科杂志,2015,(03):147-150.[doi:10.13798/j.issn.1009-153X.2015.03.006]
　HAN Li-zhi,WU Guang-yao..Analysis of MRI findings and metabolites features of intracranial demyelinating pseudotumors[J].,2015,(03):147-150.[doi:10.13798/j.issn.1009-153X.2015.03.006]
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颅内脱髓鞘假瘤磁共振影像表现与代谢物特征分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2015年03期
页码:
147-150
栏目:
论著
出版日期:
2015-03-30

文章信息/Info

Title:
Analysis of MRI findings and metabolites features of intracranial demyelinating pseudotumors
文章编号:
1009-153X（2015）03-0147-04
作者:
韩立志　吴光耀
430070 武汉，武汉大学中南医院放射科
通讯作者：吴光耀，E-mail：wuguangy2002@163.com
Author(s):
HAN Li-zhi;  WU Guang-yao.
Department of Radiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China
关键词:
颅内脱髓鞘假瘤; 磁共振成像; 诊断
Keywords:
Intracranial demyelinating pseudotumors;  MRI;  Diagnosis
分类号:
R 739.41; R 445.2
DOI:
10.13798/j.issn.1009-153X.2015.03.006
文献标志码:
A
摘要:
目的 探讨颅内脱髓鞘假瘤（IDPs）的磁共振表现与代谢物特征。方法 回顾性分析7例经病理学证实的IDPs患者影像学资料，其中平扫及增强MRI检查7、弥散加权磁共振成像检查4、磁共振波谱检查4、磁共振灌注功能成像检查2。结果 7例IDPs均表现为大脑半球单发病灶。IDPs增强MRI表现为多种强化方式共同存在，开环状强化伴垂直征、尖角征共4例，单纯开环样强化1例，闭合性环形强化1例，单纯结节样强化1例。4例弥散加权磁共振成像呈稍高信号灶、表观扩散系数下降。磁共振波谱分析示4例胆碱/N-乙酰天门冬氨酸比值升高，1例IDPs病灶显示脂质-乳酸峰。2例IDPs磁共振灌注功能成像均表现为相对脑血容量、相对脑血流量、相对平均通过时间增高。结论 IDPs增强MRI表现有特征性，认识及掌握其代谢物特征将有助于诊断该疾病。
Abstract:
Objective To explore the MRI findings and metabolites features of intracranial demyelinating pseudotumors (IDPs). Methods The MRI data of 7 patients with IDPs, of whom, all received routine MR and enhanced MR scan examinations, 4 diffusion weighted imaging (DWI) examination, 4 MR spectroscopy (MRS) examination and 2 perfusion-weighted imaging (PWI) examination, were analyzed retrospectively. Results The single irregular focus in the cerebral hemisphere of each patient was found by MRI. The multiple fashions of IDPs reinforcement existed on enhanced MRI in all the patients. The reinforcement fashions included the open loop reinforcement with vertical characters and sharp corners features in 4 patients, simple open loop reinforcement in 1, closed loop reinforcement in 1 and nodular reinforcement in 1. The high signal appeared and the value of apparent diffusion coefficient declined on DWI in 4 cases. MRS showed that the ratio of choline/N-acetyl aspartate rose in 4 cases and the lipid-lactate crest appeared in 1 case. The mean values of regional cerebral blood volume and regional cerebral blood flow, and regional mean transit time increased on PWI in 2 cases. Conclusions The manifestations of IDPs on contrast-enhanced MRI are of some characteristics. It is very helpful to the diagnosis of IDPs to understand and grasp the IDPs features of metabolites on MRI.

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更新日期/Last Update: 2015-03-30